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Publications & Studies

DR. JAVID OSAFI'S Publcations

A study of 5000 Implants in 500 Patients - A Retrospective Study with CBCT Review

Clinical Success of Megagen AnyRidge Dental Implants in Full-Arch Restorations: A Retrospective Analysis of 5000 Implants Over 800 Arches in Patients with Compromised Oral Health

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Vitamin D & Oral Cancer

In this definitive work, Dr. Javid Osafi explores a study that has been cited over 1483 times by large publications. This study reveals a link between oral cancer treatment and the use of Vitamin D. 

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5000 Dental Implants in 500 Patients

Abstract

 

This study evaluates the clinical success rate of Megagen AnyRidge dental implants in full-arch restorations across a diverse patient population, including individuals with severe periodontal disease, diabetes, and a history of smoking. Over 500 patients, involving more than 800 arches and 5000 implants, were treated with the AnyRidge system. Our analysis reveals a 99.2% success rate immediately post-surgery and a 97.5% success rate at the three-month loading period with zirconia prosthetics. These findings support the use of Megagen AnyRidge implants as a reliable solution in challenging full-arch cases.

 

Introduction

 

Dental implants have become the gold standard for full-arch rehabilitation, especially in patients with compromised oral health conditions. However, factors such as severe periodontal disease, diabetes, and smoking have historically been associated with higher implant failure rates. The Megagen AnyRidge implant system has been designed to optimize stability and support early loading, even in cases with complex conditions. This study aims to examine the success rates of the AnyRidge system in full-arch restorations under these challenging conditions.

 

Materials and Methods

 

Study Design

 

This retrospective study includes data from 500 patients who received full-arch restorations using Megagen AnyRidge dental implants between 2018 and 2023. A total of 5000 implants were placed across 800 arches.

 

Patient Population

 

The patient sample comprised individuals with various risk factors, including:

 

• Severe periodontal disease

• Diabetes mellitus

• Smoking history

 

Procedure

 

The implant placement was performed using the AnyRidge system, known for its unique thread design and high initial stability. All patients received a provisional prosthesis immediately post-surgery, followed by zirconia final restorations at the three-month mark. Clinical parameters, such as implant stability and peri-implant health, were monitored closely.

 

Outcome Measures

 

Primary outcomes assessed were:

 

• Surgical success rate (measured immediately post-surgery)

• Prosthetic success rate (measured at the three-month loading period with zirconia restorations)

 

Data Analysis

 

Success rates were calculated for each time point, with implant survival defined as the absence of mobility, pain, and infection. Statistical analysis was conducted using descriptive statistics to determine the overall success rates for this patient population.

 

Results

 

• Surgical Success Rate: Out of the 5000 implants placed, 4960 were successful immediately post-surgery, resulting in a 99.2% surgical success rate.

• Three-Month Loading Success Rate: At the three-month follow-up, when final zirconia restorations were placed, 4875 of the implants remained stable and free from complications, yielding a 97.5% success rate.

 

Patient Risk Subgroup Analysis

 

Despite the high-risk nature of the patient cohort, success rates were consistently high:

 

• Patients with severe periodontal disease: 99.1% surgical success, 97.3% loading success

• Diabetic patients: 98.9% surgical success, 97.1% loading success

• Smokers: 98.5% surgical success, 96.9% loading success

 

These results demonstrate the robustness of the AnyRidge system in achieving high success rates, even in patients traditionally considered challenging candidates for implant therapy.

 

Discussion

 

This study demonstrates that the Megagen AnyRidge implant system provides high success rates in full-arch restorations for patients with complex health conditions. The innovative design of the AnyRidge implants, particularly the tapered body and sharp thread, likely contributes to enhanced primary stability, allowing for predictable outcomes in immediate loading protocols.

 

The high success rates seen in patients with periodontal disease, diabetes, and smoking history are particularly noteworthy, as these conditions have been correlated with higher risks of implant failure. The 99.2% surgical success rate observed aligns well with other studies involving healthy patients, underscoring the potential of the AnyRidge system to support challenging cases.

 

The slight decrease in success rate at the three-month mark (97.5%) is attributed primarily to biological complications, including peri-implantitis, observed in patients with severe systemic conditions. Further research is recommended to explore specific management strategies for such complications.

 

Conclusion

 

The Megagen AnyRidge implant system achieved a 99.2% surgical success rate and a 97.5% success rate after three months in a high-risk patient population. This study supports the use of AnyRidge implants for full-arch restorations, even in patients with severe periodontal disease, diabetes, and smoking habits. The AnyRidge system proves to be a viable and reliable option for complex cases, potentially setting a new standard in implantology for compromised patients.

 

Acknowledgments

 

We extend our gratitude to the clinicians, staff, and patients who contributed to this study. Special thanks to the New Life Dental Implant Center for their commitment to advancing the field of implant dentistry.

5000 Implants in 500 Patients

Vitamin D & Oral Cancer

In a groundbreaking study, Dr. Javid Osafi and colleagues investigated the potential link between vitamin D levels and the risk of developing oral cancer. Given vitamin D’s known role in cellular health, immune response, and anti-inflammatory properties, this study explored whether sufficient vitamin D levels could serve as a protective factor against oral cancer development.

 

Study Design and Methods

 

This observational study analyzed a cohort of patients with varying vitamin D levels, assessing their relative risk of oral cancer over time. The research team measured serum vitamin D levels in patients with a history of oral cancer compared to a control group without cancer. Data were also gathered on lifestyle factors, such as diet, sun exposure, and supplement intake, which influence vitamin D levels.

 

Key Findings

 

The study revealed that:

 

1. Patients with low vitamin D levels showed a significantly higher incidence of oral cancer compared to those with adequate levels.

2. Vitamin D’s anti-inflammatory effects were associated with lower rates of cellular mutations in oral tissues, suggesting a protective mechanism against cancerous transformation.

3. High-risk groups, including smokers and those with poor dietary habits, displayed a more pronounced correlation between low vitamin D levels and oral cancer incidence, indicating that vitamin D sufficiency might be particularly beneficial for these populations.

 

Conclusions

 

Dr. Osafi and his team concluded that maintaining adequate vitamin D levels may reduce the risk of oral cancer, especially in high-risk groups. This research highlights the potential role of vitamin D as a preventive measure in oral health and underscores the need for further clinical trials to establish a causal relationship. The findings suggest that vitamin D supplementation could be a valuable addition to cancer prevention strategies, particularly for individuals at heightened risk.

 

This study, published in the Journal of Dietary Supplements, opens new avenues for exploring dietary and lifestyle modifications as preventative measures against oral cancer.

Vitamin D Study

Implant Innovations: Advancing the Future of Dentistry

Delve into the latest innovations in dental implant technology with Dr. Javid Osafi's authoritative book. Gain a deep understanding of cutting-edge procedures and materials revolutionizing the field of implant dentistry.

Implant Innovations: Advancing the Future of Dentistry

Implant Innovations: Advancing the Future of Dentistry

In the world of modern dentistry, technological advancements are transforming the way dental implant procedures are planned, executed, and restored. Innovations in digital dentistry, particularly the use of intraoral scanners and photogrammetry, have revolutionized the field, making procedures more precise, efficient, and comfortable for patients. These digital tools not only improve implant accuracy but also enhance long-term success rates, setting a new standard for the future of dental implantology.

 

The Role of Digital Dentistry in Implantology

 

Digital dentistry encompasses a range of technologies that streamline the diagnosis, treatment planning, and restorative phases of dental implant procedures. Among these, intraoral scanners and photogrammetry have become integral to achieving high precision and predictability, which are essential in complex implant cases. Here’s how these innovations contribute to advancing implant dentistry:

 

1. Intraoral Scanners: Precision and Comfort for Patients

 

Intraoral scanners have replaced traditional impression-taking techniques, which often involved messy materials and uncomfortable trays. With a handheld scanner, dentists can quickly capture a high-resolution, 3D digital impression of a patient’s mouth. These scans are crucial for implant planning, as they allow clinicians to visualize the anatomy of the mouth in detail and design custom-fitted restorations.

 

Benefits of Intraoral Scanning in Implant Dentistry:

 

• Enhanced Precision: Intraoral scanners produce accurate digital models that guide implant placement, reducing the risk of human error. This is especially beneficial in full-arch restorations, where accurate positioning is vital for function and aesthetics.

• Improved Patient Comfort: Patients benefit from a more comfortable and less invasive experience compared to traditional impressions, which can be uncomfortable, especially for those with a strong gag reflex.

• Time Efficiency: The digital workflow speeds up the treatment process. Scans are instantly available for viewing and can be sent directly to the laboratory, reducing wait times for restorations.

• Real-Time Feedback: Dentists can immediately review scans to ensure all areas are accurately captured. This minimizes the need for repeat impressions and helps ensure an ideal fit for the final restoration.

 

2. Photogrammetry: Revolutionizing Accuracy in Full-Arch Implants

 

Photogrammetry is an advanced imaging technique that captures highly accurate 3D positioning data for implants. It works by taking multiple photos from different angles to create a 3D model of the implant positions relative to each other and to surrounding structures. In full-arch restorations, where implants must be placed at precise angles and depths, photogrammetry provides unparalleled accuracy, allowing for a seamless and natural-looking final prosthesis.

 

Benefits of Photogrammetry in Dental Implants:

 

• Precision in Full-Arch Restorations: For complex cases involving multiple implants, photogrammetry captures the exact coordinates of each implant, ensuring a precise fit of the prosthesis. This level of accuracy is critical to avoid misalignments that could compromise the stability and function of the restoration.

• Minimizing Chair Time and Adjustments: Since photogrammetry data is incredibly accurate, the likelihood of needing adjustments during the final prosthesis fitting is significantly reduced. This not only saves time but also enhances patient satisfaction by reducing the need for repeated appointments.

• Long-Term Success: Accurate positioning data helps ensure that the forces applied during chewing are evenly distributed across the implants, minimizing the risk of implant failure. This precision is essential for the longevity of the restoration, as poor alignment can lead to complications such as implant loosening or bone resorption.

• Cost Efficiency: By reducing the need for adjustments and remakes, photogrammetry can ultimately save costs for both the patient and the clinic. The upfront investment in this technology is offset by the reduced time and materials needed for successful restorations.

 

Transforming the Patient Experience with Digital Dentistry

 

Digital dentistry improves not only the technical aspects of implantology but also the overall patient experience. The streamlined workflows facilitated by intraoral scanners and photogrammetry mean shorter treatment times, fewer appointments, and more predictable outcomes. For patients who may have anxieties about dental procedures, the reduction in invasive impression materials and the assurance of a precise, comfortable fit enhance the appeal of dental implant solutions.

 

The Future of Digital Innovations in Implant Dentistry

 

As digital technologies continue to evolve, implantology is likely to see even more groundbreaking innovations. Artificial intelligence (AI) is expected to play a growing role in assisting with diagnostics and treatment planning, while advancements in 3D printing are likely to make custom prosthetic designs even more accessible and cost-effective. Virtual reality (VR) and augmented reality (AR) may also enter the scene, providing immersive visualization tools that allow both patients and clinicians to understand treatment outcomes better.

 

Additionally, digital workflows improve interdisciplinary collaboration. Dentists, oral surgeons, prosthodontists, and laboratory technicians can seamlessly share digital models and treatment plans, leading to more cohesive and effective patient care.

 

Conclusion: A New Standard of Care in Implant Dentistry

 

The integration of digital tools like intraoral scanners and photogrammetry has set a new standard for accuracy, efficiency, and patient comfort in dental implantology. These innovations empower clinicians to provide customized, precise treatments that enhance the longevity and functionality of implant restorations, particularly in complex full-arch cases. As more dental practices adopt digital technologies, the future of implant dentistry promises to be one of greater accessibility, improved outcomes, and enhanced patient satisfaction.

 

In an ever-evolving field, digital dentistry’s impact on implantology underscores a commitment to innovation that is reshaping the future of dental care for patients and practitioners alike. Through ongoing advancements in digital tools and techniques, dentistry is moving towards a future where high-quality, reliable, and comfortable dental implant solutions are within reach for all patients.

FEATURED ARTICLES

A study of 5000 Implants in 500 Patients - A Retrospective Study with CBCT Review

Clinical Success of Megagen AnyRidge Dental Implants in Full-Arch Restorations: A Retrospective Analysis of 5000 Implants Over 800 Arches in Patients with Compromised Oral Health

Vitamin D & Oral Cancer - A Prospective Study In-Vitro

In this definitive work, Dr. Javid Osafi explores a study that has been cited over 1483 times by large publications. This study reveals a link between oral cancer treatment and the use of Vitamin D. 

Implant Innovations: Advancing the Future of Dentistry

Delve into the latest innovations in dental implant technology with Dr. Javid Osafi's authoritative process. Gain a deep understanding of cutting-edge procedures and materials revolutionizing the field of implant dentistry.

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